Type 2 Diabetes Clinical Pathway

Authored by Partha Kar, published on 2026-04-18 08:35:41.0

Global HbA1c Conversion ReferenceFor a global audience, targets are often expressed in two different units: Standard Percentage (%) | SI Units (mmol/mol) | Context6.5%    |    48 mmol/mol    |    Early diagnosis / Tight control 7.0%    |    53 mmol/mol    |    Standard Global Target 8.0%     |    64 mmol/mol    |    Frail / Elderly / High hypo risk

  1. DIAGNOSIS & FOUNDATION: Life/Style/Exercise 1st line: Metformin (unless contraindications) Consider SGLT2i earlier
    • DUAL THERAPY
      • If Weight is priority: Choose GLP-1 RA or GIP/GLP-1.
        • TRIPLE THERAPY
          • INTENSIFICATION
      • If Heart/Kidney priority: Choose SGLT2i or GLP-1 RA.
        • TRIPLE THERAPY
          • INTENSIFICATION
      • If Cost is priority: Choose Sulfonylurea or Pioglitazone.
        • TRIPLE THERAPY
          • INTENSIFICATION
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