Toxicity management for esophageal stricture

Authored by Nina Sanford, published on 2026-02-22 16:23:35.0

How Dr. Nina Sanford, Associate Professor and Chief of Gastrointestinal Radiation at UT Southwestern manages esophageal stricture after radiation therapy (RT). Originally posted on YouTube "Managing Toxicity from Radiotherapy to Upper GI Cancers (esophagus, pancreas, liver)" by Dr. Sanford. 

  1. Esophageal Stricture
    • Months–years post RT
      • Progressive dysphagia (solids → liquids)
        • Suspect stricture
          • Endoscopy
            • Biopsy if concerning • Confirm narrowing
            • Treatment: Serial dilation
              <p>•&nbsp;Dilation – usually requires multiple sessions (~3), done gradually to reduce risk of perforation</p><p>• Can stent if refractory</p>
              • Adequate relief?
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